Serotonin antagonist

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A serotonin antagonist is a drug used to inhibit the action at serotonin receptors.

Many of the most important medications of this class selectively act at the 5-HT3 receptor, and thus are known as 5-HT3 antagonists. However, other drugs such as ketanserin act upon other types of serotonin receptors.

Antagonists of the 5-HT2A receptor are sometimes used as atypical antipsychotics, with the typical antipsychotics being purely dopamine antagonists.

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