Alaproclate
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File:Alaproclate structure.svg | |
Systematic (IUPAC) name | |
---|---|
1-(4-chlorophenyl)-2-methylpropan-2-yl 2-aminopropanoate | |
Clinical data | |
Routes of administration | Oral |
Legal status | |
Legal status |
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Identifiers | |
CAS Number |
60719-82-6 60719-83-7 (hydrochloride) |
ATC code | N06AB07 (WHO) |
PubChem | CID 2081 |
ChemSpider | 1997 |
Chemical data | |
Formula | C13H18ClNO2 |
Molar mass | 255.740 g/mol[[Script error: No such module "String".]] |
Script error: No such module "collapsible list". | |
Alaproclate (GEA-654) is a psychoactive drug and research chemical derived from zimelidine (Normud, Zelmid) that was being developed as an antidepressant by the Swedish pharmaceutical company Astra AB (now AstraZeneca) in the 1970s. It acts as a selective serotonin reuptake inhibitor (SSRI), and along with zimelidine and indalpine, was one of the first of its kind. Development was discontinued due to the observation of liver complications in rodent studies.
See also
References
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5-HT1A Agonists | |||||||||||
H1 Antagonists | Diphenylmethanes: Captodiame • Hydroxyzine; Others: Brompheniramine • Chlorpheniramine • Pheniramine | ||||||||||
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σ1 agonists | |||||||||||
Others | Benzoctamine • Carbetocin • Demoxytocin • Mephenoxalone • Mepiprazole • Oxanamide • Oxytocin • Promoxolane • Tofisopam • Trimetozine • WAY-267,464 | ||||||||||
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