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Systematic (IUPAC) name
Clinical data
Routes of
Legal status
Legal status
  • Uncontrolled
CAS Number 60662-16-0
ATC code none
PubChem CID 42509
ChemSpider 38769
Chemical data
Formula C19H24ClN3
Molar mass 329.86696 g/mol[[Script error: No such module "String".]]
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Binedaline (Ixprim), also called binodaline, is a drug that was being investigated as an antidepressant in the 1980s but never marketed.[1][2] It acts as a selective norepinephrine reuptake inhibitor (Ki = 25 nM), with relatively insignificant influence on the serotonin (Ki = 847 nM) and dopamine (Ki >= 2 µM) transporters.[3] It has negligible affinity for the α-adrenergic, mACh, H1, or 5-HT2 receptors.[3]


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  1. Faltus; Geerling, FC (1984). "A controlled double-blind study comparing binedaline and imipramine in the treatment of endogenous depression". Neuropsychobiology. 12 (1): 34–8. doi:10.1159/000118107. PMID 6239991.  edit
  2. David J. Triggle (1996). Dictionary of Pharmacological Agents. Boca Raton: Chapman & Hall/CRC. ISBN 0-412-46630-9. 
  3. 3.0 3.1 Morin; Zini, R; Urien, S; Tillement, JP (1989). "Pharmacological profile of binedaline, a new antidepressant drug". The Journal of pharmacology and experimental therapeutics. 249 (1): 288–96. PMID 2540319.  edit