Difference between revisions of "Pargyline"
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Latest revision as of 09:57, 20 September 2010
File:Pargyline.svg | |
Systematic (IUPAC) name | |
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N-Benzyl-N-methylprop-2-yn-1-amine | |
Identifiers | |
CAS Number | 555-57-7 |
ATC code | C02KC01 (WHO) C02LL01 |
PubChem | CID 4688 |
Chemical data | |
Formula | C11H13N |
Molar mass | 159.23 g/mol[[Script error: No such module "String".]] |
(verify) |
Pargyline (Eutonyl) is a monoamine oxidase B (MAO-B) inhibitor.[1] It has antihypertensive effects.[2]
Pharmacology
It functions by inhibiting the metabolism of catecholamines and tyramine within presynaptic nerve terminals. Patients taking pargyline must avoid concurrent consumption of tyramine-containing foods such as blue cheese and beer, as this can lead to a hypertensive crisis.[3]
References
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40px | This antihypertensive-related article is a stub. You can help ssf by expanding it. |
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- ↑ Murphy DL, Karoum F, Pickar D; et al. (1998). "Differential trace amine alterations in individuals receiving acetylenic inhibitors of MAO-A (clorgyline) or MAO-B (selegiline and pargyline)". J. Neural Transm. Suppl. 52: 39–48. PMID 9564606. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
- ↑ Lua error in package.lua at line 80: module 'Module:Citation/CS1/Suggestions' not found.
- ↑ Tulane University School of Medicine Department of Pharmacology: Autonomic Drug Profile handout, October 2006
Retrieved from "http://ssf.f15ijp.com/wiki/index.php?title=Pargyline&oldid=31769"
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