|Systematic (IUPAC) name|
|Molar mass||245.727 g/mol[[Script error: No such module "String".]]|
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EMD-386,088 is an indole derivative which is used in scientific research. It acts as a potent and selective 5-HT6 receptor agonist, with a Ki of 1 nM, a significantly higher affinity than older 5-HT6 agonists such as EMDT, although it possesses moderate affinity for the 5-HT3 receptor as well.
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- Mattsson C, Sonesson C, Sandahl A, Greiner HE, Gassen M, Plaschke J, Leibrock J, Böttcher H. 2-Alkyl-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indoles as novel 5-HT6 receptor agonists. Bioorganic and Medicinal Chemistry Letters. 2005; 15(19):4230-4234. PMID 16055331