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File:Binospirone 3D.gif
Systematic (IUPAC) name
CAS Number 124756-23-6
ATC code none
PubChem CID 60769
Chemical data
Formula C20H26N2O4
Molar mass 358.431 g/mol[[Script error: No such module "String".]]
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Binospirone (MDL-73,005-EF) is a drug which acts as a partial agonist at 5-HT1A somatodendritic autoreceptors but as an antagonist at postsynaptic 5-HT1A receptors.[1] It has anxiolytic effects.[2]

See also


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  1. Bertrand F, Lehmann O, Galani R, Lazarus C, Jeltsch H, Cassel JC. Effects of MDL 73005 on water-maze performances and locomotor activity in scopolamine-treated rats. Pharmacology, Biochemistry and Behaviour. 2001 Apr;68(4):647-60. PMID 11526961
  2. Moser PC, Tricklebank MD, Middlemiss DN, Mir AK, Hibert MF, Fozard JR. Characterization of MDL 73005EF as a 5-HT1A selective ligand and its effects in animal models of anxiety: comparison with buspirone, 8-OH-DPAT and diazepam. British Journal of Pharmacology. 1990 Feb;99(2):343-9. PMID 1970269