Dazopride

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Dazopride
File:Dazopride.png
Systematic (IUPAC) name
4-amino-5-chloro-N-(1,2-diethylpyrazolidin-4-yl)-2-methoxy-benzamide
Clinical data
Routes of
administration
Oral
Legal status
Legal status
  • Uncontrolled
Identifiers
CAS Number 70181-03-2
ATC code none
PubChem CID 54801
ChemSpider 49487
Chemical data
Formula C15H23ClN4O2
Molar mass 326.82 g/mol[[Script error: No such module "String".]]
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Dazopride (AHR-5531) is an antiemetic and gastroprokinetic agent of the benzamide class which was never marketed.[1][2][3][4][5] It acts as a 5-HT3 receptor antagonist and 5-HT4 receptor agonist.[3][4][6] In addition to its gastrointestinal effects, dazopride facilitates learning and memory in mice.[7]

See also

References

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pt:Dazoprida
  1. Grant SC, Kris MG, Gralla RJ, Clark RA, Tyson LB (1993). "Dose-ranging evaluation of the substituted benzamide dazopride when used as an antiemetic in patients receiving anticancer chemotherapy". Cancer Chemotherapy and Pharmacology. 31 (6): 442–4. PMID 8453682. 
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  5. David J. Triggle (1996). Dictionary of Pharmacological Agents. Boca Raton: Chapman & Hall/CRC. ISBN 0-412-46630-9. 
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  7. Montgomery, S. A.; Halbreich, Uriel (2000). Pharmacotherapy for mood, anxiety, and cognitive disorders. Washington, DC: American Psychiatric Press. ISBN 0-88048-885-9.