F-15,599

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F-15,599
File:F-15599-structure.png
Systematic (IUPAC) name
3-chloro-4-fluorophenyl-[4-fluoro-4-[[(5-methylpyrimidin-2-ylmethyl)amino]methyl]piperidin-1-yl]methanone
Clinical data
Routes of
administration		 Oral
Legal status
Legal status
  • Uncontrolled
Identifiers
CAS Number ?
ATC code none
PubChem CID ?
Chemical data
Formula C19H22ClF2N4O
Molar mass 395.854 g/mol[[Script error: No such module "String".]]
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F-15,599 is a very potent and highly selective 5-HT1A receptor full agonist.[1][2] It displays functional selectivity by strongly activating 5-HT1A receptors in the prefrontal cortex while having little effect on autoreceptors in the raphe nucleus.[1][2] As a result, it has been touted as a preferential postsynaptic 5-HT1A receptor agonist and is being investigated as a novel potential antidepressant.[1][2]

See also

References

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GABAA PAMs
Others
α2δ VDCC Blockers
5-HT1A Agonists
Azapirones: Buspirone • Gepirone • Tandospirone; Others: Flesinoxan • Oxaflozane
H1 Antagonists
Diphenylmethanes: Captodiame • Hydroxyzine; Others: Brompheniramine • Chlorpheniramine • Pheniramine
CRH1 Antagonists
NK2 Antagonists
MCH1 antagonists
mGluR2/3 Agonists
mGluR5 NAMs
TSPO agonists
σ1 agonists
Others

M: PSO/PSI

dsrd (o, p, m, p, a, d, s), sysi/epon, spvo

proc, drug(N5A/5B/5C/6A/6B/6D)


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  1. ↑ 1.0 1.1 1.2 Lua error in package.lua at line 80: module 'Module:Citation/CS1/Suggestions' not found.
  2. ↑ 2.0 2.1 2.2 Lua error in package.lua at line 80: module 'Module:Citation/CS1/Suggestions' not found.
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