6-Methyl-MDA

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6-Methyl-MDA
File:6-Methyl-MDA.png
Systematic (IUPAC) name
1-(6-methyl-1,3-benzodioxol-5-yl)propan-2-amine
Clinical data
Routes of
administration
Oral
Legal status
Legal status
Identifiers
ATC code none
PubChem CID 10511982
ChemSpider 8687383
Chemical data
Formula C11NO2
Molar mass 193.24 g/mol[[Script error: No such module "String".]]
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2-Methyl-4,5-methylenedioxyamphetamine (6-Methyl-MDA) is an entactogen and psychedelic drug of the amphetamine class.[1] It was first synthesized in the late 1990s by a team including David E. Nichols at Purdue University while investigating derivatives of MDA and MDMA.[1]

6-Methyl-MDA has IC50 values of 783 nM, 28,300 nM, and 4,602 nM for inhibiting the reuptake of serotonin, dopamine, and norepinephrine in rat synaptosomes.[1] In animal studies it substitutes for MBDB, MMAI, LSD, and DOI, though not amphetamine, but only partially and at high doses.[1] Thus, while several-fold less potent than its analogues 2-methyl-MDA and 5-methyl-MDA, and approximately half as potent as MDA, 6-methyl-MDA is still significantly active,[1] and appropriate doses may be similar to or somewhat higher than those of MDMA.[citation needed]

See also

References

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