Volinanserin
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File:MDL-100,907 structure.png | |
Systematic (IUPAC) name | |
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(R)-(2,3-dimethoxyphenyl)-[1-[2-(4-fluorophenyl)ethyl]-4-piperidyl]methanol | |
Identifiers | |
CAS Number | 139290-65-6 |
ATC code | none |
PubChem | CID 5311271 |
IUPHAR/BPS | 185 |
ChemSpider | 4470782 |
Chemical data | |
Formula | C22H28FNO3 |
Molar mass | 373.46 g/mol[[Script error: No such module "String".]] |
Script error: No such module "collapsible list". | |
Volinanserin (MDL-100,907) is a highly selective 5-HT2A receptor antagonist. It is widely used in scientific research to investigate the function of the 5-HT2A receptor.[1][2][3] Volinanserin is also being trialed as a potential antipsychotic, antidepressant and treatment for insomnia.[4][5][6]
See also
References
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Antipsychotics (neuroleptics) (N05A) | |||
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Typical | Benzamides: Levosulpiride • Nemonapride • Sulpiride • Sultopride • Tiapride • Veralipride; Butyrophenones: Azaperone • Benperidol • Bromperidol • Droperidol • Fluanisone • Haloperidol • Lenperone • Moperone • Pipamperone • Spiperone • Timiperone • Trifluperidol; Diphenylbutylpiperidines: Clopimozide • Fluspirilene • Penfluridol • Pimozide; Phenothiazines: Acepromazine • Acetophenazine • Butaperazine • Carphenazine • Chloracizine • Chlorproethazine • Chlorpromazine • Cyamemazine • Dixyrazine • Fluacizine • Fluphenazine • Levomepromazine/Methotrimeprazine • Mesoridazine • Perazine • Periciazine • Perphenazine • Piperacetazine • Pipotiazine • Prochlorperazine • Promazine • Promethazine • Propiomazine • Sulforidazine • Thiethylperazine • Thiopropazate • Thioproperazine • Thioridazine • Trifluoperazine • Triflupromazine; Thioxanthenes: Chlorprothixene • Clopenthixol • Flupentixol • Thiothixene • Zuclopenthixol; Tricyclics: Amoxapine • Butaclamol • Fluotracen • Loxapine • Metitepine/Methiothepin • Octoclothiepin • Trimipramine; Others: Prothipendyl | ||
Atypical | Benzamides: Amisulpride • Remoxipride; Butyrophenones: Cinuperone • Setoperone; Benzo(iso)oxazolepiperidines: Iloperidone • Ocaperidone • Paliperidone • Risperidone; Benzo(iso)thiazolepiperazines: Lurasidone • Perospirone • Revospirone • Tiospirone • Ziprasidone; Diphenylbutylpiperazines: Amperozide; Phenylpiperazines: Aripiprazole • Bifeprunox • Elopiprazole • Umespirone; Tricyclics: Asenapine • Carpipramine • Clocapramine • Clotiapine • Clozapine • Fluperlapine • Gevotroline • Metitepine/Methiothepin • Mosapramine • NDMC • Olanzapine • Piquindone • Quetiapine • Tenilapine • Zotepine; Others: Blonanserin • Cariprazine • Molindone • Pimavanserin • Roxindole • Sarizotan • Sertindole • Spiramide | ||
Others | Azacyclonol • Cannabidiol • D-Cycloserine • Lithium • Mifepristone • Oxypertine • Reserpine • Rimcazole • Secretin • Talnetant • Tetrabenazine • Vabicaserin | ||
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GABAA receptor |
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Alpha-2 adrenergic receptor |
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Melatonin receptor | |||||||||||||||||||||||||||||
Histamine receptor & Acetylcholine receptor | |||||||||||||||||||||||||||||
5-HT2A & α1-adrenergic |
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GABAB receptor / GHB receptor |
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Orexin receptors |
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Other receptors/ ungrouped |
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- ↑ Teegarden BR, Al Shamma H, Xiong Y (2008). "5-HT(2A) inverse-agonists for the treatment of insomnia". Current Topics in Medicinal Chemistry. 8 (11): 969–76. doi:10.2174/156802608784936700. PMID 18673166. CS1 maint: Multiple names: authors list (link)
Retrieved from "http://ssf.f15ijp.com/wiki/index.php?title=Volinanserin&oldid=22750"
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