Dazopride
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File:Dazopride.png | |
Systematic (IUPAC) name | |
---|---|
4-amino-5-chloro-N-(1,2-diethylpyrazolidin-4-yl)-2-methoxy-benzamide | |
Clinical data | |
Routes of administration | Oral |
Legal status | |
Legal status |
|
Identifiers | |
CAS Number | 70181-03-2 |
ATC code | none |
PubChem | CID 54801 |
ChemSpider | 49487 |
Chemical data | |
Formula | C15H23ClN4O2 |
Molar mass | 326.82 g/mol[[Script error: No such module "String".]] |
Dazopride (AHR-5531) is an antiemetic and gastroprokinetic agent of the benzamide class which was never marketed.[1][2][3][4][5] It acts as a 5-HT3 receptor antagonist and 5-HT4 receptor agonist.[3][4][6] In addition to its gastrointestinal effects, dazopride facilitates learning and memory in mice.[7]
See also
References
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- ↑ Grant SC, Kris MG, Gralla RJ, Clark RA, Tyson LB (1993). "Dose-ranging evaluation of the substituted benzamide dazopride when used as an antiemetic in patients receiving anticancer chemotherapy". Cancer Chemotherapy and Pharmacology. 31 (6): 442–4. PMID 8453682.
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- ↑ David J. Triggle (1996). Dictionary of Pharmacological Agents. Boca Raton: Chapman & Hall/CRC. ISBN 0-412-46630-9.
- ↑ Lua error in package.lua at line 80: module 'Module:Citation/CS1/Suggestions' not found.
- ↑ Montgomery, S. A.; Halbreich, Uriel (2000). Pharmacotherapy for mood, anxiety, and cognitive disorders. Washington, DC: American Psychiatric Press. ISBN 0-88048-885-9.
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