RS-67,333
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| File:RS 67333.png | |
| Systematic (IUPAC) name | |
|---|---|
|
1-(4-amino-5-chloro-2-methoxyphenyl)-3-(1-butyl-4-piperidinyl)-1-propanone | |
| Identifiers | |
| CAS Number | 160845-95-4 |
| Chemical data | |
| Formula | C19H29N2O2Cl |
| Molar mass | 352.9 g/mol |
| Script error: No such module "collapsible list". | |
RS-67,333 is an psychoactive drug and research chemical being investigated as a potential rapid-acting antidepressant,[1] nootropic,[2] and treatment for Alzheimer's disease.[3] It is a high-affinity 5-HT4 receptor partial agonist, as well as sigma receptor ligand with preference for the σ1 subtype.[4]
References
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| Anticholinesterases | |||
|---|---|---|---|
| Others | Bifemelane • Bilobalide (Ginkgo Biloba) • Ensaculin • Latrepirdine • Lecozotan • Leteprinim • Memantine • Semagacestat | ||
| Acetylcholinesterases | |
|---|---|
| Ampakines | |
| D1 Agonists | |
| Eugeroics | |
| GABAA α5 Inverse Agonists | |
| H3 Antagonists | |
| mACh Agonists | Alvameline • Arecoline • Cevimeline • CI-1017 • Milameline • Sabcomeline • Talsaclidine • Tazomeline • Xanomeline |
| nACh Agonists | |
| Racetams | |
| Others | Acetylcarnitine • Adafenoxate • Bifemelane • Bilobalide (Ginkgo Biloba) • Carbenoxolone • Choline (Lecithin) • Citicoline • Cyprodenate • Dimethylethanolamine • Ensaculin • Fipexide • Idebenone • Latrepirdine • Leteprinim • Linopirdine • Meclofenoxate • Nizofenone • Pirisudanol • Pyritinol • S-17092 • Sulbutiamine • Taltirelin • Tricyanoaminopropene • Vinpocetine |
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| 35px | This drug article relating to the nervous system is a stub. You can help ssf by expanding it. |
- ↑ Lucas G, Rymar VV, Du J, Mnie-Filali O, Bisgaard C, Manta S, Lambas-Senas L, Wiborg O, Haddjeri N, Piñeyro G, Sadikot AF, Debonnel G. (2007). "Serotonin(4) (5-HT(4)) Receptor Agonists Are Putative Antidepressants with a Rapid Onset of Action". Neuron. 55 (5): 712–25. doi:10.1016/j.neuron.2007.07.041. PMID 17785179. CS1 maint: Multiple names: authors list (link)
- ↑ Lamirault L, Simon H. (2001). "Enhancement of place and object recognition memory in young adult and old rats by RS 67333, a partial agonist of 5-HT4 receptors". Neuropharmacology. 41 (7): 844–53. doi:10.1016/S0028-3908(01)00123-X. PMID 11684148.
- ↑ Cho S, Hu Y. (2007). "Activation of 5-HT4 receptors inhibits secretion of beta-amyloid peptides and increases neuronal survival". Experimental Neurology. 203 (1): 274–8. doi:10.1016/j.expneurol.2006.07.021. PMID 16978609.
- ↑ Lua error in package.lua at line 80: module 'Module:Citation/CS1/Suggestions' not found.
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