CSP-2503
From Self-sufficiency
Revision as of 02:22, 26 August 2010 by حسن علي البط (Talk) (Removed Category:Pyrazines; Adding category Category:Lactams (using HotCat))
(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to: navigation, search
| File:CSP-2503-structure.png | |
| Systematic (IUPAC) name | |
|---|---|
|
2-[(4-naphthalen-1-ylpiperazin-1-yl)methyl]hexahydropyrrolo[1,2-a]pyrazine-1,4-dione | |
| Identifiers | |
| CAS Number | ? |
| ATC code | none |
| PubChem | CID 10317515 |
| ChemSpider | 8492979 |
| Chemical data | |
| Formula | C22H26N4O2 |
| Molar mass | 378.47 g/mol[[Script error: No such module "String".]] |
CSP-2503 is a potent and selective 5-HT1A receptor agonist, 5-HT2A receptor antagonist, and 5-HT3 receptor antagonist of the phenylpiperazine class.[1] First synthesized in 2003, it was designed based on computational models and QSAR studies.[2][3] In rat studies, CSP-2503 has demonstrated anxiolytic effects, and thus has been suggested as a treatment for anxiety in humans with a multimodal mechanism of action.[1]
See also
References
Cite error: Invalid <references> tag;
parameter "group" is allowed only.
<references />, or <references group="..." />
| GABAA PAMs |
| ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| α2δ VDCC Blockers | |||||||||||
| 5-HT1A Agonists | |||||||||||
| H1 Antagonists | Diphenylmethanes: Captodiame • Hydroxyzine; Others: Brompheniramine • Chlorpheniramine • Pheniramine | ||||||||||
| CRH1 Antagonists | |||||||||||
| NK2 Antagonists | |||||||||||
| MCH1 antagonists | |||||||||||
| mGluR2/3 Agonists | |||||||||||
| mGluR5 NAMs | |||||||||||
| TSPO agonists | |||||||||||
| σ1 agonists | |||||||||||
| Others | Benzoctamine • Carbetocin • Demoxytocin • Mephenoxalone • Mepiprazole • Oxanamide • Oxytocin • Promoxolane • Tofisopam • Trimetozine • WAY-267,464 | ||||||||||
| |||||||||||
| Simple piperazines (no additional rings) | |
|---|---|
| Phenylpiperazines | Acaprazine • Antrafenine • Aripiprazole • Batoprazine • Bifeprunox • BRL-15,572 • Ciprofloxacin • CSP-2503 • Dapiprazole • DCPP • DMPP • Dropropizine • EGIS-12,233 • Elopiprazole • Eltoprazine • Enpiprazole • Ensaculin • Etoperidone • Flesinoxan • Flibanserin • Fluprazine • Itraconazole • Ketoconazole • Levodropropizine • Lorpiprazole • mCPP • MeOPP • Mepiprazole • Naftopidil • Naphthylpiperazine • Nefazodone • Niaprazine • Oxypertine • Pardoprunox • pCPP • pFPP • Posaconazole • PRX-00023 • S-14,506 • S-14,671 • S-15,535 • SB-258,585 • SB-271,046 • SB-357,134 • SB-399,885 • Sonepiprazole • TFMPP • Tolpiprazole • Trazodone • Urapidil • Vesnarinone • Vilazodone • WAY-100,135 • WAY-100,635 |
| Benzylpiperazines | 2C-B-BZP • Befuraline • Bifeprunox • Buclizine • BZP • Chlorbenzoxamine • DBZP • Fipexide • Imatinib • MBZP • MDBZP • Meclozine • Piberaline • Piribedil • Trimetazidine • Vesnarinone |
| Diphenylalkylpiperazines (benzhydrylalkylpiperazines) | Almitrine • Amperozide • BRL-15,572 • Buclizine • BW373U86 • Cetirizine • Chlorbenzoxamine • Chlorcyclizine • Cinnarizine • Clocinizine • Cyclizine • DBL-583 • Diphenylmethylpiperazine • Dotarizine • DPI-221 • DPI-287 • DPI-3290 • GBR-12,783 • GBR-12,935 • GBR-13,069 • GBR-13,098 • GBR-13,119 • Hydroxyzine • Lidoflazine • Manidipine • Meclozine • Oxatomide • SNC-80 • Vanoxerine |
| Pyrimidinylpiperazines | Buspirone • Dasatinib • Eptapirone • Gepirone • Ipsapirone • Piribedil • Pyrimidinylpiperazine • Revospirone • Tandospirone • Tirilazad • Trimazosin • Umespirone • Zalospirone |
| Pyridinylpiperazines | |
| Benzo(iso)thiazolylpiperazines | |
| Tricyclics (piperazine attached via side chain) | |
| Others | 6-Nitroquipazine • Azimilide • Cinepazet • Cyclohexylpiperazine • Hexocyclium • Indinavir • JNJ-7777120 • Lodenafil • Mirodenafil • PB-28 • Quipazine • Ranolazine • SA-4503 • Sildenafil • Tadalafil • Vardenafil • VUF-6002 • Zipeprol |
Retrieved from "http://ssf.f15ijp.com/wiki/index.php?title=CSP-2503&oldid=24023"
Categories:
- Pages with script errors
- Pages with broken file links
- Infobox drug tracked parameters
- Articles without EBI source
- Chemical pages without DrugBank identifier
- Articles without KEGG source
- Articles without InChI source
- Articles without UNII source
- Drugs not assigned an ATC code
- Drugs with no legal status
- Articles containing unverified chemical infoboxes
- Naphthalenes
- Piperazines
- Pyrrolopyrazines
- Lactams
- 2Fix
