Isamoltane

Isamoltane
	File:Isamoltane.png
Systematic (IUPAC) name
	1-(propan-2-ylamino)-3-(2-pyrrol-1-ylphenoxy)propan-2-ol
Identifiers
CAS Number	99740-06-4
ATC code	none
PubChem	CID 127403
Chemical data
Formula	C16H22N2O2
Molar mass	274.357 g/mol[[Script error: No such module "String".]]
	Script error: No such module "collapsible list".

Script error: No such module "TemplatePar".Expression error: Unexpected < operator.

Isamoltane (CGP-361A) is a drug used in scientific research. It acts as an antagonist at the β-adrenergic, 5-HT_1A, and 5-HT_1B receptors. It has about five times the potency for the 5-HT_1B receptor (21 nmol/l) over the 5-HT_1A receptor (112 nmol/l).^[1] It has anxiolytic effects in rodents.^[2]

References

Cite error: Invalid <references> tag; parameter "group" is allowed only.

Use <references />, or <references group="..." />

↑ Rényi L, Larsson LG, Berg S, Svensson BE, Thorell G, Ross SB. (1991). "Biochemical and behavioural effects of isamoltane, a beta-adrenoceptor antagonist with affinity for the 5-HT1B receptor of rat brain". Naunyn Schmiedebergs Arch Pharmacol. 343 (1): 1–6. PMID 1674359.
↑ Waldmeier PC, Williams M, Baumann PA, Bischoff S, Sills MA, Neale RF. (1988). "Interactions of isamoltane (CGP 361A), an anxiolytic phenoxypropanolamine derivative, with 5-HT1 receptor subtypes in the rat brain". Naunyn Schmiedebergs Arch Pharmacol. 337 (6): 609–620. PMID 2905765.