Pridefine

Pridefine
	File:Pridefine.png
Systematic (IUPAC) name
	3-(diphenylmethylidene)-1-ethylpyrrolidine
Clinical data
Routes of; administration	Oral
Legal status
Legal status	Uncontrolled;
Identifiers
CAS Number	5370-41-2
ATC code	none
PubChem	CID 31740
ChemSpider	29434
Chemical data
Formula	C19H21N
Molar mass	263.38 g/mol[[Script error: No such module "String".]]

Script error: No such module "TemplatePar".Expression error: Unexpected < operator.

Pridefine (AHR-1,118) is a drug which was investigated as an antidepressant in the late 1970s and early 1980s but was never marketed.^[1] It acts as a balanced reuptake inhibitor of serotonin, dopamine, and norepinephrine, and also has some weak releasing activity.^[2]^[1]^[3]

In clinical trials pridefine was found to be as efficacious as the tricyclic antidepressants amitriptyline and imipramine in the treatment of major depressive disorder but was much more tolerable in comparison and also had an earlier onset of action.^[1] It has been shown to be effective in the treatment of alcoholism as well.^[1]

References

Cite error: Invalid <references> tag; parameter "group" is allowed only.

Use <references />, or <references group="..." />

↑ ^1.0 ^1.1 ^1.2 ^1.3 Lua error in package.lua at line 80: module 'Module:Citation/CS1/Suggestions' not found.
↑ Halaris AE, Demet EM (1980). "Open trial evaluation of a pyrrolidine derivative (AHR-1118) on norepinephrine metabolism". Progress in Neuro-psychopharmacology. 4 (1): 43–9. PMID 7406986.
↑ Lua error in package.lua at line 80: module 'Module:Citation/CS1/Suggestions' not found.