Brain-specific angiogenesis inhibitor 3

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Brain-specific angiogenesis inhibitor 3
Identifiers
Symbols	BAI3; KIAA0550; MGC133100
External IDs	OMIM: 602684 MGI: 2441837 HomoloGene: 1289 IUPHAR: BAI3 GeneCards: BAI3 Gene
Gene Ontology Molecular function • receptor activity • G-protein coupled receptor activity • brain-specific angiogenesis inhibitor activity Cellular component • cell surface • membrane • integral to membrane Biological process • signal transduction • neuropeptide signaling pathway Sources: Amigo / EGO
Orthologs
Species	Human	Mouse
Entrez	577	210933
Ensembl	ENSG00000135298	ENSMUSG00000033569
UniProt	O60242	Q499E3
RefSeq (mRNA)	NM_001704	NM_175642
RefSeq (protein)	NP_001695	NP_783573
Location (UCSC)	Chr 6: 69.4 - 70.16 Mb	Chr 1: 25.01 - 25.77 Mb
PubMed search	[1]	[2]

Brain-specific angiogenesis inhibitor 3 is a protein that in humans is encoded by the BAI3 gene.

BAI1, a p53-target gene, encodes brain-specific angiogenesis inhibitor, a seven-span transmembrane protein and is thought to be a member of the secretin receptor family. Brain-specific angiogenesis proteins BAI2 and BAI3 are similar to BAI1 in structure, have similar tissue specificities and may also play a role in angiogenesis.

Further reading

• Nakajima D, Okazaki N, Yamakawa H; et al. (2003). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones". DNA Res. 9 (3): 99–106. doi:10.1093/dnares/9.3.99. PMID 12168954. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Nagase T, Ishikawa K, Miyajima N; et al. (1998). "Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Res. 5 (1): 31–9. doi:10.1093/dnares/5.1.31. PMID 9628581. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241 Freely accessible. PMID 12477932. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Bjarnadóttir TK, Fredriksson R, Höglund PJ; et al. (2005). "The human and mouse repertoire of the adhesion family of G-protein-coupled receptors". Genomics. 84 (1): 23–33. doi:10.1016/j.ygeno.2003.12.004. PMID 15203201. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 Freely accessible. PMID 15489334. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.