GPR1
From Self-sufficiency
| edit |
| G protein-coupled receptor 1 | |||||||||||||
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| Identifiers | |||||||||||||
| Symbols | GPR1; | ||||||||||||
| External IDs | OMIM: 600239 MGI: 2385324 HomoloGene: 21094 IUPHAR: GPR1 GeneCards: GPR1 Gene | ||||||||||||
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| RNA expression pattern | |||||||||||||
| 250px | |||||||||||||
| More reference expression data | |||||||||||||
| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 2825 | 241070 | |||||||||||
| Ensembl | ENSG00000183671 | ENSMUSG00000046856 | |||||||||||
| UniProt | P46091 | Q8K087 | |||||||||||
| RefSeq (mRNA) | NM_005279 | NM_146250 | |||||||||||
| RefSeq (protein) | NP_005270 | NP_666362 | |||||||||||
| Location (UCSC) | Chr 2: 206.75 - 206.79 Mb | Chr 1: 63.12 - 63.15 Mb | |||||||||||
| PubMed search | [1] | [2] | |||||||||||
G protein-coupled receptor 1, also known as GPR1, is a protein that in humans is encoded by the GPR1 gene.[1][2]
GPR1 is a member of the G protein-coupled receptor family of transmembrane receptors. It functions as a receptor for chemerin. [3] Other receptors for chemerin include CMKLR1 and CCRL2.
References
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<references />, or <references group="..." />Further reading
- Shimizu N, Soda Y, Kanbe K; et al. (1999). "An orphan G protein-coupled receptor, GPR1, acts as a coreceptor to allow replication of human immunodeficiency virus types 1 and 2 in brain-derived cells". J. Virol. 73 (6): 5231–9. PMC 112576 Freely accessible. PMID 10233994.
- Tokizawa S, Shimizu N, Hui-Yu L; et al. (2000). "Infection of mesangial cells with HIV and SIV: identification of GPR1 as a coreceptor". Kidney Int. 58 (2): 607–17. doi:10.1046/j.1523-1755.2000.00207.x. PMID 10916084.
- Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241 Freely accessible. PMID 12477932.
- Kang MK, Kameta A, Shin KH; et al. (2003). "Senescence-associated genes in normal human oral keratinocytes". Exp. Cell Res. 287 (2): 272–81. doi:10.1016/S0014-4827(03)00061-2. PMID 12837283.
- Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 Freely accessible. PMID 15489334.
- Hillier LW, Graves TA, Fulton RS; et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4". Nature. 434 (7034): 724–31. doi:10.1038/nature03466. PMID 15815621.
- Jinno-Oue A, Shimizu N, Soda Y; et al. (2005). "The synthetic peptide derived from the NH2-terminal extracellular region of an orphan G protein-coupled receptor, GPR1, preferentially inhibits infection of X4 HIV-1". J. Biol. Chem. 280 (35): 30924–34. doi:10.1074/jbc.M500195200. PMID 15919664.
- Otsuki T, Ota T, Nishikawa T; et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Res. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743.
- Kimura K, Wakamatsu A, Suzuki Y; et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129 Freely accessible. PMID 16344560.
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- ↑ "Entrez Gene: GPR1 G protein-coupled receptor 1".
- ↑ Lua error in package.lua at line 80: module 'Module:Citation/CS1/Suggestions' not found.
- ↑ Lua error in package.lua at line 80: module 'Module:Citation/CS1/Suggestions' not found.
