LPHN3

From Self-sufficiency
Jump to: navigation, search
edit
Latrophilin 3
Identifiers
SymbolsLPHN3; CIRL3; LEC3
External IDsMGI2441950 HomoloGene22878 IUPHAR: LPHN3 GeneCards: LPHN3 Gene
Orthologs
SpeciesHumanMouse
Entrez23284319387
EnsemblENSG00000150471ENSMUSG00000037605
UniProtQ9HAR2Q80TS3
RefSeq (mRNA)NM_015236NM_198702
RefSeq (protein)NP_056051NP_941991
Location (UCSC)Chr 4:
62.05 - 62.62 Mb
Chr 5:
82.1 - 82.87 Mb
PubMed search[1][2]

Latrophilin-3 is a protein that in humans is encoded by the LPHN3 gene.[1][2]

This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane.[2]

See also

References

Cite error: Invalid <references> tag; parameter "group" is allowed only.

Use <references />, or <references group="..." />

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

  1. Lua error in package.lua at line 80: module 'Module:Citation/CS1/Suggestions' not found.
  2. 2.0 2.1 "Entrez Gene: LPHN3 latrophilin 3".