Glucagon-like peptide 2 receptor

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Glucagon-like peptide 2 receptor
Identifiers
Symbols	GLP2R;
External IDs	OMIM: 603659 MGI: 2136733 HomoloGene: 3132 IUPHAR: GLP-2 GeneCards: GLP2R Gene
Gene Ontology Molecular function • receptor activity • G-protein coupled receptor activity Cellular component • plasma membrane • membrane • integral to membrane Biological process • signal transduction • G-protein coupled receptor protein signaling pathway • G-protein signaling, coupled to cAMP nucleotide second messenger • positive regulation of cell proliferation Sources: Amigo / EGO
RNA expression pattern
250px
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	9340	93896
Ensembl	ENSG00000065325	n/a
UniProt	O95838	n/a
RefSeq (mRNA)	NM_004246	XM_991784
RefSeq (protein)	NP_004237	XP_996878
Location (UCSC)	Chr 17: 9.67 - 9.73 Mb	n/a
PubMed search	[1]	[2]

The gene for the glucagon-like peptide 2 receptor (GLP-2) is on chromosome 17.

See also

• Glucagon-like peptide-2

Further reading

• Burrin DG, Petersen Y, Stoll B, Sangild P (2001). "Glucagon-like peptide 2: a nutrient-responsive gut growth factor". J. Nutr. 131 (3): 709–12. PMID 11238747. CS1 maint: Multiple names: authors list (link)
• Munroe DG, Gupta AK, Kooshesh F; et al. (1999). "Prototypic G protein-coupled receptor for the intestinotrophic factor glucagon-like peptide 2". Proc. Natl. Acad. Sci. U.S.A. 96 (4): 1569–73. doi:10.1073/pnas.96.4.1569. PMC 15520 Freely accessible. PMID 9990065. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Yusta B, Huang L, Munroe D; et al. (2000). "Enteroendocrine localization of GLP-2 receptor expression in humans and rodents". Gastroenterology. 119 (3): 744–55. doi:10.1053/gast.2000.16489. PMID 10982769. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Thulesen J, Knudsen LB, Hartmann B; et al. (2002). "The truncated metabolite GLP-2 (3-33) interacts with the GLP-2 receptor as a partial agonist". Regul. Pept. 103 (1): 9–15. doi:10.1016/S0167-0115(01)00316-0. PMID 11738243. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241 Freely accessible. PMID 12477932. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Koehler JA, Yusta B, Drucker DJ (2005). "The HeLa cell glucagon-like peptide-2 receptor is coupled to regulation of apoptosis and ERK1/2 activation through divergent signaling pathways". Mol. Endocrinol. 19 (2): 459–73. doi:10.1210/me.2004-0196. PMID 15471943. CS1 maint: Multiple names: authors list (link)
• Ørskov C, Hartmann B, Poulsen SS; et al. (2005). "GLP-2 stimulates colonic growth via KGF, released by subepithelial myofibroblasts with GLP-2 receptors". Regul. Pept. 124 (1-3): 105–12. doi:10.1016/j.regpep.2004.07.009. PMID 15544847. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Mahon MJ, Shimada M (2005). "Calmodulin interacts with the cytoplasmic tails of the parathyroid hormone 1 receptor and a sub-set of class b G-protein coupled receptors". FEBS Lett. 579 (3): 803–7. doi:10.1016/j.febslet.2004.12.056. PMID 15670850. 
• Estall JL, Koehler JA, Yusta B, Drucker DJ (2005). "The glucagon-like peptide-2 receptor C terminus modulates beta-arrestin-2 association but is dispensable for ligand-induced desensitization, endocytosis, and G-protein-dependent effector activation". J. Biol. Chem. 280 (23): 22124–34. doi:10.1074/jbc.M500078200. PMID 15817468. CS1 maint: Multiple names: authors list (link)
• Guan X, Karpen HE, Stephens J; et al. (2006). "GLP-2 receptor localizes to enteric neurons and endocrine cells expressing vasoactive peptides and mediates increased blood flow". Gastroenterology. 130 (1): 150–64. doi:10.1053/j.gastro.2005.11.005. PMID 16401478. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Sams A, Hastrup S, Andersen M, Thim L (2006). "Naturally occurring glucagon-like peptide-2 (GLP-2) receptors in human intestinal cell lines". Eur. J. Pharmacol. 532 (1-2): 18–23. doi:10.1016/j.ejphar.2005.12.001. PMID 16448646. CS1 maint: Multiple names: authors list (link)

External links

• "Glucagon Receptor Family: GLP-2". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. 
• MeSH glucagon-like+peptide+receptor