EMR3

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Egf-like module containing, mucin-like, hormone receptor-like 3
Identifiers
SymbolsEMR3;
External IDsOMIM606101 HomoloGene50009 IUPHAR: EMR3 GeneCards: EMR3 Gene
RNA expression pattern
250px
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez84658n/a
EnsemblENSG00000131355n/a
UniProtQ9BY15n/a
RefSeq (mRNA)NM_032571n/a
RefSeq (protein)NP_115960n/a
Location (UCSC)Chr 19:
14.57 - 14.65 Mb
n/a
PubMed search[1]n/a

EGF-like module-containing mucin-like hormone receptor-like 3 is a protein that in humans is encoded by the EMR3 gene.[1][2][3]

This gene encodes a member of the class B seven-span transmembrane (TM7) receptor family expressed predominantly by cells of the immune system. Family members are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor (EGF)-like domains coupled to a TM7 domain via a mucin-like spacer domain. This gene is closely linked to the gene encoding egf-like molecule containing mucin-like hormone receptor 2 on chromosome 19. This protein may play a role in myeloid-myeloid interactions during immune and inflammatory responses.[3]

See also

References

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Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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  3. 3.0 3.1 "Entrez Gene: EMR3 egf-like module containing, mucin-like, hormone receptor-like 3".