Cysteinyl leukotriene receptor 2

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Cysteinyl leukotriene receptor 2
Identifiers
SymbolsCYSLTR2; GPCR; CYSLT2; CYSLT2R; HG57; HPN321; KPG_011; PSEC0146; hGPCR21
External IDsOMIM605666 MGI1917336 HomoloGene10688 IUPHAR: CysLT2 GeneCards: CYSLTR2 Gene
RNA expression pattern
250px
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez5710570086
EnsemblENSG00000152207ENSMUSG00000033470
UniProtQ9NS75Q8R528
RefSeq (mRNA)NM_020377NM_133720
RefSeq (protein)NP_065110NP_598481
Location (UCSC)Chr 13:
48.18 - 48.18 Mb
Chr 14:
71.76 - 71.78 Mb
PubMed search[1][2]

Cysteinyl leukotriene receptor 2 is a protein that in humans is encoded by the CYSLTR2 gene.[1][2][3]

The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, the protein encoded by this gene and CYSLTR1. This encoded receptor is a member of the superfamily of G protein-coupled receptors. It seems to play a major role in endocrine and cardiovascular systems.[3]

See also

References

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External links

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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