TAS2R16

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Taste receptor, type 2, member 16
Identifiers
SymbolsTAS2R16; T2R16
External IDsOMIM604867 MGI2681247 HomoloGene9660 GeneCards: TAS2R16 Gene
RNA expression pattern
250px
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez50833387347
EnsemblENSG00000128519ENSMUSG00000043865
UniProtQ9NYV7A0AUK2
RefSeq (mRNA)NM_016945NM_207022
RefSeq (protein)NP_058641NP_996905
Location (UCSC)Chr 7:
122.42 - 122.42 Mb
Chr 6:
23.92 - 23.92 Mb
PubMed search[1][2]

TAS2R16 (taste receptor, type 2, member 16) is a human gene that encodes for a receptor that may play a role in the perception of bitterness. [1][2]

Variants of this gene have been linked to an increased risk for alcohol dependence.[3]

The TAS2R16 gene is located on the long (q) arm of chromosome 7 at position 31.1 - 31.3, from base pair 122,228,764 to base pair 122,229,639.

See also

References

  1. Bufe B, Hofmann T, Krautwurst D, Raguse JD, Meyerhof W (2002). "The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides". Nat Genet. 32 (3): 397–401. doi:10.1038/ng1014. PMID 12379855. 
  2. Drewnowski A (2001). "The science and complexity of bitter taste". Nutr Rev. 59 (6): 163–9. doi:10.1111/j.1753-4887.2001.tb07007.x. PMID 11444592. 
  3. Hinrichs AL, Wang JC, Bufe B; et al. (2006). "Functional variant in a bitter-taste receptor (hTAS2R16) influences risk of alcohol dependence". Am. J. Hum. Genet. 78 (1): 103–11. doi:10.1086/499253. PMC 1380207Freely accessible. PMID 16385453. 

Further reading

External links