GABBR2

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Gamma-aminobutyric acid (GABA) B receptor, 2
Identifiers
SymbolsGABBR2; FLJ36928; GABABR2; GPR51; GPRC3B; HG20
External IDsOMIM607340 MGI2386030 HomoloGene55902 IUPHAR: GABAB2 GeneCards: GABBR2 Gene
RNA expression pattern
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More reference expression data
Orthologs
SpeciesHumanMouse
Entrez9568242425
EnsemblENSG00000136928ENSMUSG00000039809
UniProtO75899Q80T41
RefSeq (mRNA)NM_005458XM_143750
RefSeq (protein)NP_005449XP_143750
Location (UCSC)Chr 9:
100.09 - 100.51 Mb
Chr 4:
46.68 - 47 Mb
PubMed search[1][2]

Gamma-aminobutyric acid (GABA) B receptor, 2 (GABAB2) is a G-protein coupled receptor subunit encoded by the GABBR2 gene in humans.[1]

B-type receptors for the neurotransmitter GABA (gamma-aminobutyric acid) inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters and the activity of ion channels and adenylyl cyclase. See GABBR1 (MIM 603540) for additional background information on GABA-B receptors.[supplied by OMIM][1]

Interactions

GABBR2 has been shown to interact with GABBR1.[2]

See also

References

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External links

  • "GABAB Receptors: GABAB2". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. 

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

ru:GABBR2
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