FZD1

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Frizzled homolog 1 (Drosophila)
Identifiers
SymbolsFZD1; DKFZp564G072
External IDsOMIM603408 MGI1196625 HomoloGene20750 IUPHAR: FZD1 GeneCards: FZD1 Gene
RNA expression pattern
250px
250px
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez832114362
EnsemblENSG00000157240ENSMUSG00000044674
UniProtQ9UP38Q7TS82
RefSeq (mRNA)NM_003505NM_021457
RefSeq (protein)NP_003496NP_067432
Location (UCSC)Chr 7:
90.73 - 90.74 Mb
Chr 5:
4.76 - 4.76 Mb
PubMed search[1][2]

Frizzled-1 is a protein that in humans is encoded by the FZD1 gene.[1][2]

Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD1 protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-terminal PDZ domain-binding motif. The FZD1 transcript is expressed in various tissues.[2]

See also

References

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External links

  • "Frizzled Receptors: FZD1". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. 

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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  2. 2.0 2.1 "Entrez Gene: FZD1 frizzled homolog 1 (Drosophila)".