OPN5

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Opsin 5
Identifiers
Symbols	OPN5; GPR136; PGR12; TMEM13
External IDs	OMIM: 609042 MGI: 2662912 HomoloGene: 72341 IUPHAR: OPN5 GeneCards: OPN5 Gene
Gene Ontology Molecular function • rhodopsin-like receptor activity • receptor activity Cellular component • membrane • integral to membrane Biological process • signal transduction • G-protein coupled receptor protein signaling pathway • visual perception • phototransduction • protein-chromophore linkage • response to stimulus Sources: Amigo / EGO
Orthologs
Species	Human	Mouse
Entrez	221391	353344
Ensembl	ENSG00000124818	ENSMUSG00000043972
UniProt	Q6U736	Q059L5
RefSeq (mRNA)	NM_001030051	NM_181753
RefSeq (protein)	NP_001025222	NP_861418
Location (UCSC)	Chr 6: 47.86 - 47.9 Mb	Chr 17: 42.02 - 42.07 Mb
PubMed search	[1]	[2]

Opsin-5 is a protein that in humans is encoded by the OPN5 gene.

Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. This opsin gene is expressed in the eye, brain, testes, and spinal cord. This gene belongs to the seven-exon subfamily of mammalian opsin genes that includes peropsin (RRH) and retinal G protein coupled receptor (RGR). Like these other seven-exon opsin genes, this gene may encode a protein with photoisomerase activity. Alternative splicing results in multiple transcript variants encoding different isoforms.

See also

• Opsin

Further reading

• Terakita A (2006). "The opsins". Genome Biol. 6 (3): 213. doi:10.1186/gb-2005-6-3-213. PMC 1088937 Freely accessible. PMID 15774036. 
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241 Freely accessible. PMID 12477932. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Vassilatis DK, Hohmann JG, Zeng H; et al. (2003). "The G protein-coupled receptor repertoires of human and mouse". Proc. Natl. Acad. Sci. U.S.A. 100 (8): 4903–8. doi:10.1073/pnas.0230374100. PMC 153653 Freely accessible. PMID 12679517. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Mungall AJ, Palmer SA, Sims SK; et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. doi:10.1038/nature02055. PMID 14574404. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 Freely accessible. PMID 15489334. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.