GPR6

From Self-sufficiency
Jump to: navigation, search
edit
G protein-coupled receptor 6
Identifiers
SymbolsGPR6;
External IDsOMIM600553 MGI2155249 HomoloGene38026 IUPHAR: GPR6 GeneCards: GPR6 Gene
RNA expression pattern
250px
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez2830140741
EnsemblENSG00000146360ENSMUSG00000046922
UniProtP46095Q2M2N8
RefSeq (mRNA)NM_005284NM_199058
RefSeq (protein)NP_005275NP_951013
Location (UCSC)Chr 6:
110.41 - 110.41 Mb
Chr 10:
40.76 - 40.76 Mb
PubMed search[1][2]

G protein-coupled receptor 6, also known as GPR6, is a protein which in humans is encoded by the GPR6 gene.[1][2]

Function

GPR6 is a member of the G protein-coupled receptor family of transmembrane receptors. It has been reported that GPR6 is both constitutively active but in addition is further activated by sphingosine-1-phosphate.[3]

GPR6 up-regulates cyclic AMP levels and promotes neurite outgrowth.[4]

See also

References

Cite error: Invalid <references> tag; parameter "group" is allowed only.

Use <references />, or <references group="..." />

Further reading

External links

  • "GPR6". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. 


  1. "Entrez Gene: GPR6 G protein-coupled receptor 6". 
  2. Lua error in package.lua at line 80: module 'Module:Citation/CS1/Suggestions' not found.
  3. Lua error in package.lua at line 80: module 'Module:Citation/CS1/Suggestions' not found.
  4. Lua error in package.lua at line 80: module 'Module:Citation/CS1/Suggestions' not found.