GPR156

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G protein-coupled receptor 156
Identifiers
Symbols	GPR156; GABABL; MGC142261; PGR28
External IDs	OMIM: 610464 MGI: 2653880 HomoloGene: 17683 IUPHAR: GPR156 GeneCards: GPR156 Gene
Gene Ontology Molecular function • receptor activity • GABA-B receptor activity Cellular component • plasma membrane • integral to membrane Biological process • signal transduction • G-protein coupled receptor protein signaling pathway Sources: Amigo / EGO
RNA expression pattern
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More reference expression data
Orthologs
Species	Human	Mouse
Entrez	165829	239845
Ensembl	ENSG00000175697	ENSMUSG00000046961
UniProt	Q8NFN8	Q6PCP7
RefSeq (mRNA)	NM_153002	NM_153394
RefSeq (protein)	NP_694547	NP_700443
Location (UCSC)	Chr 3: 121.36 - 121.45 Mb	Chr 16: 37.84 - 37.93 Mb
PubMed search	[1]	[2]

GPR156 (G protein-coupled receptor 156), is a human gene which encodes a G protein-coupled receptor belonging to metabotropic glutamate receptor subfamily. By sequence homology, this gene was proposed as being a possible GABA_B receptor subunit, however when expressed in cells alone or with other GABA_B subunits, no response to GABA_B ligands could be detected. Therefore the function of this protein remains to be elucidated.

Further reading

• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241 Freely accessible. PMID 12477932. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Calver AR, Michalovich D, Testa TT; et al. (2003). "Molecular cloning and characterisation of a novel GABAB-related G-protein coupled receptor". Brain Res. Mol. Brain Res. 110 (2): 305–17. doi:10.1016/S0169-328X(02)00662-9. PMID 12591167. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Vassilatis DK, Hohmann JG, Zeng H; et al. (2003). "The G protein-coupled receptor repertoires of human and mouse". Proc. Natl. Acad. Sci. U.S.A. 100 (8): 4903–8. doi:10.1073/pnas.0230374100. PMC 153653 Freely accessible. PMID 12679517. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 Freely accessible. PMID 15489334. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)