GPR98

From Self-sufficiency
Jump to: navigation, search
edit
G protein-coupled receptor 98
Identifiers
SymbolsGPR98; USH2B; DKFZp761P0710; FEB4; KIAA0686; MASS1; USH2C; VLGR1; VLGR1b
External IDsOMIM602851 MGI1274784 HomoloGene19815 IUPHAR: GPR98 GeneCards: GPR98 Gene
RNA expression pattern
250px
250px
250px
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez84059110789
EnsemblENSG00000164199ENSMUSG00000069170
UniProtQ8WXG9Q8C1E5
RefSeq (mRNA)NM_032119NM_054053
RefSeq (protein)NP_115495NP_473394
Location (UCSC)Chr 5:
89.95 - 90.5 Mb
Chr 13:
81.56 - 82.07 Mb
PubMed search[1][2]

G protein-coupled receptor 98, also known as GPR98, is a human protein and gene.[1]

This gene encodes a member of the G-protein coupled receptor superfamily. The protein binds calcium and is expressed in the central nervous system. It is also known as very large G-protein coupled receptor 1 because it is 6300 residues long. It contains a C-terminal 7-transmembrane receptor domain, whereas the large N-terminal segment (5900 residues) includes 35 calcium binding Calx-beta domains, and 6 EAR domains. Mutations in this gene are associated with Usher syndrome 2 and familial febrile seizures. Several alternatively spliced transcripts have been described.[1]

External Links

References

Cite error: Invalid <references> tag; parameter "group" is allowed only.

Use <references />, or <references group="..." />

Further reading

  1. 1.0 1.1 "Entrez Gene: GPR98 G protein-coupled receptor 98".