MRGPRX2

MAS-related GPR, member X2
Identifiers
Symbols	MRGPRX2; MRGX2
External IDs	OMIM: 607228 MGI: 3588270 HomoloGene: 24986 IUPHAR: MRGPRX2 GeneCards: MRGPRX2 Gene
Gene Ontology
Molecular function	• rhodopsin-like receptor activity; • receptor activity; • neuropeptide binding;
Cellular component	• membrane; • integral to membrane;
Biological process	• signal transduction; • G-protein coupled receptor protein signaling pathway; • sensory perception of pain; • sleep;
	Sources: Amigo / EGO
Orthologs

Mas-related G-protein coupled receptor member X2 is a protein that in humans is encoded by the MRGPRX2 gene.^[1]^[2]

References

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Takeda S, Kadowaki S, Haga T; et al. (2002). "Identification of G protein-coupled receptor genes from the human genome sequence". FEBS Lett. 520 (1-3): 97–101. doi:10.1016/S0014-5793(02)02775-8. PMID 12044878.
Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241 Freely accessible. PMID 12477932.
Robas N, Mead E, Fidock M (2004). "MrgX2 is a high potency cortistatin receptor expressed in dorsal root ganglion". J. Biol. Chem. 278 (45): 44400–4. doi:10.1074/jbc.M302456200. PMID 12915402.
Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 Freely accessible. PMID 15489334.
Yang S, Liu Y, Lin AA; et al. (2005). "Adaptive evolution of MRGX2, a human sensory neuron specific gene involved in nociception". Gene. 352: 30–5. doi:10.1016/j.gene.2005.03.001. PMID 15862286.

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↑ "Entrez Gene: MRGPRX2 MAS-related GPR, member X2".