5-HT1F receptor

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5-hydroxytryptamine (serotonin) receptor 1F
SymbolsHTR1F; 5-HT1F; HTR1EL; MR77
External IDsOMIM182134 MGI99842 HomoloGene37361 IUPHAR: 5-HT1F GeneCards: HTR1F Gene
RNA expression pattern
More reference expression data
RefSeq (mRNA)NM_000866NM_008310
RefSeq (protein)NP_000857NP_032336
Location (UCSC)Chr 3:
88.12 - 88.12 Mb
Chr 16:
64.87 - 65.05 Mb
PubMed search[1][2]

5-hydroxytryptamine (serotonin) receptor 1F, also known as HTR1F is a 5-HT1 receptor protein and also denotes the human gene encoding it.[1][2][3][4][5]




No selective 5HT1F antagonists are available as yet.

See also


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External links

  • "5-HT1F". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. 

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

  1. "Entrez Gene: HTR1F 5-hydroxytryptamine (serotonin) receptor 1F". 
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  4. Erdmann J, Shimron-Abarbanell D, Shridhar V, Smith DI, Propping P, Nöthen MM (1997). "Assignment of the human serotonin 1F receptor gene (HTR1F) to the short arm of chromosome 3 (3p13-p14.1)". Mol. Membr. Biol. 14 (3): 133–5. doi:10.3109/09687689709048173. PMID 9394293. 
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  6. Wainscott DB, Krushinski JH, Audia JE, Schaus JM, Zgombick JM, Lucaites VL, Nelson DL (2005). "[3H]-LY-334,370, a novel radioligand for the 5-HT1F receptor. I. In vitro characterization of binding properties". Naunyn Schmiedebergs Arch. Pharmacol. 371 (3): 169–77. doi:10.1007/s00210-005-1035-9. PMID 15900510. 
  7. Zhang D, Kohlman D, Krushinski J, Liang S, Ying BP, Reilly JE, Dinn SR, Wainscott DB, Nutter S, Gough W, Nelson DL, Schaus JM, Xu YC (2004). "Design, synthesis and evaluation of bicyclic benzamides as novel 5-HT1F receptor agonists". Bioorg. Med. Chem. Lett. 14 (24): 6011–6. doi:10.1016/j.bmcl.2004.09.079. PMID 15546719.