TAAR1

edit

Trace amine associated receptor 1
Identifiers
Symbols	TAAR1; MGC126874; MGC138399; RP11-295F4.9; TA1; TAR1; TRAR1
External IDs	OMIM: 609333 MGI: 2148258 HomoloGene: 24938 IUPHAR: TA1 GeneCards: TAAR1 Gene
Gene Ontology Molecular function • trace-amine receptor activity • receptor activity Cellular component • membrane • integral to membrane Biological process • signal transduction • G-protein coupled receptor protein signaling pathway Sources: Amigo / EGO
RNA expression pattern
250px
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	134864	111174
Ensembl	ENSG00000146399	ENSMUSG00000056379
UniProt	Q96RJ0	Q05A85
RefSeq (mRNA)	NM_138327	NM_053205
RefSeq (protein)	NP_612200	NP_444435
Location (UCSC)	Chr 6: 133.01 - 133.01 Mb	Chr 10: 23.61 - 23.61 Mb
PubMed search	[1]	[2]

Trace amine-associated receptor 1 is a protein that in humans is encoded by the TAAR1 gene.

TAAR1 is a G protein-coupled receptor activated by trace amines. Trace amines are endogenous amine compounds that account for less than 1% of the biogenic amines in most brain regions (Bunzow et al., 2001).[supplied by OMIM]

See also

• Trace amine-associated receptor

Further reading

• Bunzow JR, Sonders MS, Arttamangkul S; et al. (2001). "Amphetamine, 3,4-methylenedioxymethamphetamine, lysergic acid diethylamide, and metabolites of the catecholamine neurotransmitters are agonists of a rat trace amine receptor". Mol. Pharmacol. 60 (6): 1181–8. PMID 11723224. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241 Freely accessible. PMID 12477932. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Mungall AJ, Palmer SA, Sims SK; et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. doi:10.1038/nature02055. PMID 14574404. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 Freely accessible. PMID 15489334. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.