GPR132

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G protein-coupled receptor 132
Identifiers
SymbolsGPR132; G2A; MGC99642
External IDsOMIM606167 MGI1890220 HomoloGene8350 IUPHAR: GPR132 GeneCards: GPR132 Gene
RNA expression pattern
250px
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez2993356696
EnsemblENSG00000183484ENSMUSG00000021298
UniProtQ9UNW8Q0VBS4
RefSeq (mRNA)NM_013345NM_019925
RefSeq (protein)NP_037477NP_064309
Location (UCSC)Chr 14:
104.59 - 104.6 Mb
Chr 12:
113.3 - 113.31 Mb
PubMed search[1][2]

Probable G-protein coupled receptor 132 is a protein that in humans is encoded by the GPR132 gene.[1][2]

This gene encodes a subfamily member of the G-protein couple receptor (GPCR) superfamily. The encoded protein is a high-affinity receptor for lysophosphatidylcholine (LPC), a major phospholipid component of oxidized low density lipoprotein. This protein may react to LPC levels at sites of inflammation to limit the expansion of tissue-infiltrating cells. A similar protein in mouse is involved in cell cycle progression.[2]

See also

References

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Further reading


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  2. 2.0 2.1 "Entrez Gene: GPR132 G protein-coupled receptor 132".