TAS1R1

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Taste receptor, type 1, member 1
Identifiers
SymbolsTAS1R1; TR1; GPR70; T1R1; gm148
External IDsOMIM606225 MGI1927505 HomoloGene12888 GeneCards: TAS1R1 Gene
Orthologs
SpeciesHumanMouse
Entrez80835110326
EnsemblENSG00000173662ENSMUSG00000028950
UniProtQ7RTX1Q3U5H1
RefSeq (mRNA)NM_138697NM_031867
RefSeq (protein)NP_619642NP_114073
Location (UCSC)Chr 1:
6.54 - 6.56 Mb
Chr 4:
150.87 - 150.88 Mb
PubMed search[1][2]

Taste receptor type 1 member 1 is a protein that in humans is encoded by the TAS1R1 gene.[1]

The protein encoded by this gene is a G protein-coupled receptor and is a component of the heterodimeric amino acid taste receptor T1R1+3. The T1R1+3 receptor responds to L-amino acids but not to D-enantiomers or other compounds. Most amino acids that are perceived as sweet activate T1R1+3, and this activation is strictly dependent on an intact T1R1+3 heterodimer. Multiple transcript variants encoding several different isoforms have been found for this gene.[1]

See also

References

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Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

  1. 1.0 1.1 "Entrez Gene: TAS1R1 taste receptor, type 1, member 1".