GPR124

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G protein-coupled receptor 124
Identifiers
Symbols	GPR124; DKFZp434C211; DKFZp434J0911; FLJ14390; KIAA1531; TEM5
External IDs	OMIM: 606823 MGI: 1925810 HomoloGene: 13112 IUPHAR: GPR124 GeneCards: GPR124 Gene
Gene Ontology Molecular function • receptor activity • G-protein coupled receptor activity • protein binding Cellular component • membrane • integral to membrane Biological process • signal transduction • neuropeptide signaling pathway Sources: Amigo / EGO
RNA expression pattern
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More reference expression data
Orthologs
Species	Human	Mouse
Entrez	25960	78560
Ensembl	ENSG00000020181	ENSMUSG00000031486
UniProt	Q96PE1	Q91ZV8
RefSeq (mRNA)	NM_032777	NM_054044
RefSeq (protein)	NP_116166	NP_473385
Location (UCSC)	Chr 8: 37.77 - 37.82 Mb	Chr 8: 28.55 - 28.59 Mb
PubMed search	[1]	[2]

Probable G-protein coupled receptor 124 is a protein that in humans is encoded by the GPR124 gene.

Interactions

GPR124 has been shown to interact with DLG1.

Further reading

• Nakajima D, Okazaki N, Yamakawa H; et al. (2003). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones". DNA Res. 9 (3): 99–106. doi:10.1093/dnares/9.3.99. PMID 12168954. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Nagase T, Kikuno R, Ishikawa K; et al. (2000). "Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 7 (2): 143–50. doi:10.1093/dnares/7.2.143. PMID 10819331. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241 Freely accessible. PMID 12477932. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Yamamoto Y, Irie K, Asada M; et al. (2004). "Direct binding of the human homologue of the Drosophila disc large tumor suppressor gene to seven-pass transmembrane proteins, tumor endothelial marker 5 (TEM5), and a novel TEM5-like protein". Oncogene. 23 (22): 3889–97. doi:10.1038/sj.onc.1207495. PMID 15021905. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Bjarnadóttir TK, Fredriksson R, Höglund PJ; et al. (2005). "The human and mouse repertoire of the adhesion family of G-protein-coupled receptors". Genomics. 84 (1): 23–33. doi:10.1016/j.ygeno.2003.12.004. PMID 15203201. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Vallon M, Essler M (2006). "Proteolytically processed soluble tumor endothelial marker (TEM) 5 mediates endothelial cell survival during angiogenesis by linking integrin alpha(v)beta3 to glycosaminoglycans". J. Biol. Chem. 281 (45): 34179–88. doi:10.1074/jbc.M605291200. PMID 16982628.