MRGPRX3

MAS-related GPR, member X3
Identifiers
Symbols	MRGPRX3; GPCR; MRGX3; SNSR1
External IDs	OMIM: 607229 MGI: 3644999 HomoloGene: 79615 IUPHAR: MRGPRX3 GeneCards: MRGPRX3 Gene
Gene Ontology
Molecular function	• rhodopsin-like receptor activity; • receptor activity;
Cellular component	• membrane; • integral to membrane;
Biological process	• signal transduction; • G-protein coupled receptor protein signaling pathway;
	Sources: Amigo / EGO
Orthologs

Mas-related G-protein coupled receptor member X3 is a protein that in humans is encoded by the MRGPRX3 gene.^[1]^[2]

References

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Lembo PM, Grazzini E, Groblewski T; et al. (2002). "Proenkephalin A gene products activate a new family of sensory neuron--specific GPCRs". Nat. Neurosci. 5 (3): 201–9. doi:10.1038/nn815. PMID 11850634.
Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241 Freely accessible. PMID 12477932.
Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 Freely accessible. PMID 15489334.
Kaisho Y, Watanabe T, Nakata M; et al. (2005). "Transgenic rats overexpressing the human MrgX3 gene show cataracts and an abnormal skin phenotype". Biochem. Biophys. Res. Commun. 330 (3): 653–7. doi:10.1016/j.bbrc.2005.03.027. PMID 15809047.

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↑ "Entrez Gene: MRGPRX3 MAS-related GPR, member X3".