P2RY14

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Purinergic receptor P2Y, G-protein coupled, 14
Identifiers
SymbolsP2RY14; GPR105; KIAA0001; P2Y14
External IDsOMIM610116 MGI2155705 HomoloGene15769 IUPHAR: P2Y14 GeneCards: P2RY14 Gene
RNA expression pattern
250px
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez9934140795
EnsemblENSG00000174944ENSMUSG00000036381
UniProtQ15391Q544F4
RefSeq (mRNA)NM_001081455NM_001008497
RefSeq (protein)NP_001074924NP_001008497
Location (UCSC)Chr 3:
152.41 - 152.48 Mb
Chr 3:
59.2 - 59.22 Mb
PubMed search[1][2]

P2Y purinoceptor 14 is a protein that in humans is encoded by the P2RY14 gene.[1]

The product of this gene, P2Y14 belongs to the family of G-protein coupled receptors, which contains several receptor subtypes with different pharmacological selectivity for various adenosine and uridine nucleotides. This receptor is a P2Y purinergic receptor for UDP-glucose and other UDP-sugars coupled to G-proteins. It has been implicated in extending the known immune system functions of P2Y receptors by participating in the regulation of the stem cell compartment, and it may also play a role in neuroimmune function. Two transcript variants encoding the same protein have been identified for this gene.[1]

See also

References

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External links

  • "P2Y Receptors: P2Y14". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. 

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

pt:P2RY14
  1. 1.0 1.1 "Entrez Gene: P2RY14 purinergic receptor P2Y, G-protein coupled, 14".