GPR78

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G protein-coupled receptor 78
Identifiers
Symbols	GPR78;
External IDs	OMIM: 606921 HomoloGene: 50960 IUPHAR: GPR78 GeneCards: GPR78 Gene
Gene Ontology Molecular function • rhodopsin-like receptor activity • receptor activity Cellular component • membrane • integral to membrane Biological process • signal transduction • G-protein coupled receptor protein signaling pathway Sources: Amigo / EGO
Orthologs
Species	Human	Mouse
Entrez	27201	n/a
Ensembl	ENSG00000155269	n/a
UniProt	Q96P69	n/a
RefSeq (mRNA)	NM_080819	n/a
RefSeq (protein)	NP_543009	n/a
Location (UCSC)	Chr 4: 8.63 - 8.64 Mb	n/a
PubMed search	[1]	n/a

Probable G-protein coupled receptor 78 is a protein that in humans is encoded by the GPR78 gene.

G protein-coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins.[supplied by OMIM]

Further reading

• van Laar T, Schouten T, Hoogervorst E; et al. (2000). "The novel MMS-inducible gene Mif1/KIAA0025 is a target of the unfolded protein response pathway". FEBS Lett. 469 (1): 123–31. doi:10.1016/S0014-5793(00)01253-9. PMID 10708769. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241 Freely accessible. PMID 12477932. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Clark HF, Gurney AL, Abaya E; et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697 Freely accessible. PMID 12975309. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 Freely accessible. PMID 15489334. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Underwood SL, Christoforou A, Thomson PA; et al. (2006). "Association analysis of the chromosome 4p-located G protein-coupled receptor 78 (GPR78) gene in bipolar affective disorder and schizophrenia". Mol. Psychiatry. 11 (4): 384–94. doi:10.1038/sj.mp.4001786. PMID 16389273. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)