Neuromedin U receptor 2

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Neuromedin U receptor 2
Identifiers
Symbols	NMUR2; FM4; NMU2R
External IDs	OMIM: 605108 MGI: 2441765 HomoloGene: 49618 IUPHAR: NMU2 GeneCards: NMUR2 Gene
Gene Ontology Molecular function • rhodopsin-like receptor activity • neuromedin U receptor activity • receptor activity • intracellular calcium activated chloride channel activity • GTP binding Cellular component • integral to plasma membrane • membrane Biological process • calcium ion transport • regulation of smooth muscle contraction • signal transduction • G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) • elevation of cytosolic calcium ion concentration • neuropeptide signaling pathway • central nervous system development • feeding behavior • transmission of nerve impulse • calcium-dependent phospholipase A2 activation • secretory pathway • inositol phosphate-mediated signaling • arachidonic acid secretion Sources: Amigo / EGO
Orthologs
Species	Human	Mouse
Entrez	56923	216749
Ensembl	ENSG00000132911	ENSMUSG00000037393
UniProt	Q9GZQ4	Q8BZ39
RefSeq (mRNA)	NM_020167	NM_153079
RefSeq (protein)	NP_064552	NP_694719
Location (UCSC)	Chr 5: 151.75 - 151.77 Mb	Chr 11: 55.87 - 55.88 Mb
PubMed search	[1]	[2]

Neuromedin-U receptor 2 is a protein that in humans is encoded by the NMUR2 gene.

See also

• Neuromedin U receptor

External links

• "Neuromedin U Receptors: NMU2". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. 

Further reading

• Hosoya M, Moriya T, Kawamata Y; et al. (2000). "Identification and functional characterization of a novel subtype of neuromedin U receptor". J. Biol. Chem. 275 (38): 29528–32. doi:10.1074/jbc.M004261200. PMID 10887190. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Raddatz R, Wilson AE, Artymyshyn R; et al. (2000). "Identification and characterization of two neuromedin U receptors differentially expressed in peripheral tissues and the central nervous system". J. Biol. Chem. 275 (42): 32452–9. doi:10.1074/jbc.M004613200. PMID 10899166. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Shan L, Qiao X, Crona JH; et al. (2001). "Identification of a novel neuromedin U receptor subtype expressed in the central nervous system". J. Biol. Chem. 275 (50): 39482–6. doi:10.1074/jbc.C000522200. PMID 11010960. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Fernández Alvarez C, Debeljuk L, Díaz Rodríguez E, Díaz López B (2003). "Developmental pattern of tachykinins during aging in several organs: effect of exogenous melatonin". Peptides. 23 (9): 1617–23. doi:10.1016/S0196-9781(02)00099-2. PMID 12217422. CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241 Freely accessible. PMID 12477932. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 Freely accessible. PMID 15489334. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Bhattacharyya S, Luan J, Farooqi IS; et al. (2004). "Studies of the neuromedin U-2 receptor gene in human obesity: evidence for the existence of two ancestral forms of the receptor". J. Endocrinol. 183 (1): 115–20. doi:10.1677/joe.1.05830. PMID 15525579. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Mori K, Miyazato M, Ida T; et al. (2005). "Identification of neuromedin S and its possible role in the mammalian circadian oscillator system". EMBO J. 24 (2): 325–35. doi:10.1038/sj.emboj.7600526. PMC 545815 Freely accessible. PMID 15635449. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Fang L, Zhang M, Li C; et al. (2006). "Chemical genetic analysis reveals the effects of NMU2R on the expression of peptide hormones". Neurosci. Lett. 404 (1-2): 148–53. doi:10.1016/j.neulet.2006.05.034. PMID 16781063. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)