GPRC5C
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| G protein-coupled receptor, family C, group 5, member C | |||||||||||||
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| Identifiers | |||||||||||||
| Symbols | GPRC5C; MGC131820; RAIG-3; RAIG3 | ||||||||||||
| External IDs | OMIM: 605949 MGI: 1917605 HomoloGene: 11099 IUPHAR: RAIG3 GeneCards: GPRC5C Gene | ||||||||||||
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| RNA expression pattern | |||||||||||||
| 250px | |||||||||||||
| More reference expression data | |||||||||||||
| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 55890 | 70355 | |||||||||||
| Ensembl | ENSG00000170412 | ENSMUSG00000051043 | |||||||||||
| UniProt | Q9NQ84 | Q8CEU2 | |||||||||||
| RefSeq (mRNA) | NM_018653 | XM_973134 | |||||||||||
| RefSeq (protein) | NP_061123 | XP_978228 | |||||||||||
| Location (UCSC) | Chr 17: 69.94 - 69.96 Mb | Chr 11: 114.67 - 114.69 Mb | |||||||||||
| PubMed search | [1] | [2] | |||||||||||
G-protein coupled receptor family C group 5 member C is a protein that in humans is encoded by the GPRC5C gene.[1][2]
The protein encoded by this gene is a member of the type 3 G protein-coupled receptor family. Members of this superfamily are characterized by a signature 7-transmembrane domain motif. The specific function of this protein is unknown; however, this protein may mediate the cellular effects of retinoic acid on the G protein signal transduction cascade. Two transcript variants encoding different isoforms have been found for this gene.[2]
See also
References
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<references />, or <references group="..." />External links
- "GPRC5 Receptors: RAIG3". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology.
Further reading
- Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1-2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
- Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K; et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1-2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
- Bräuner-Osborne H, Krogsgaard-Larsen P (2000). "Sequence and expression pattern of a novel human orphan G-protein-coupled receptor, GPRC5B, a family C receptor with a short amino-terminal domain". Genomics. 65 (2): 121–8. doi:10.1006/geno.2000.6164. PMID 10783259.
- Bräuner-Osborne H, Jensen AA, Sheppard PO; et al. (2001). "Cloning and characterization of a human orphan family C G-protein coupled receptor GPRC5D". Biochim. Biophys. Acta. 1518 (3): 237–48. PMID 11311935.
- Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241 Freely accessible. PMID 12477932.
- Lehner B, Semple JI, Brown SE; et al. (2004). "Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region". Genomics. 83 (1): 153–67. doi:10.1016/S0888-7543(03)00235-0. PMID 14667819.
- Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 Freely accessible. PMID 15489334.
- Rual JF, Venkatesan K, Hao T; et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
- Otsuki T, Ota T, Nishikawa T; et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Res. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743.
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This article incorporates text from the United States National Library of Medicine, which is in the public domain.
- ↑ Lua error in package.lua at line 80: module 'Module:Citation/CS1/Suggestions' not found.
- ↑ 2.0 2.1 "Entrez Gene: GPRC5C G protein-coupled receptor, family C, group 5, member C".
