GPR156
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G protein-coupled receptor 156 | |||||||||||||
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Identifiers | |||||||||||||
Symbols | GPR156; GABABL; MGC142261; PGR28 | ||||||||||||
External IDs | OMIM: 610464 MGI: 2653880 HomoloGene: 17683 IUPHAR: GPR156 GeneCards: GPR156 Gene | ||||||||||||
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RNA expression pattern | |||||||||||||
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More reference expression data | |||||||||||||
Orthologs | |||||||||||||
Species | Human | Mouse | |||||||||||
Entrez | 165829 | 239845 | |||||||||||
Ensembl | ENSG00000175697 | ENSMUSG00000046961 | |||||||||||
UniProt | Q8NFN8 | Q6PCP7 | |||||||||||
RefSeq (mRNA) | NM_153002 | NM_153394 | |||||||||||
RefSeq (protein) | NP_694547 | NP_700443 | |||||||||||
Location (UCSC) | Chr 3: 121.36 - 121.45 Mb | Chr 16: 37.84 - 37.93 Mb | |||||||||||
PubMed search | [1] | [2] |
GPR156 (G protein-coupled receptor 156), is a human gene which encodes a G protein-coupled receptor belonging to metabotropic glutamate receptor subfamily.[1] By sequence homology, this gene was proposed as being a possible GABAB receptor subunit, however when expressed in cells alone or with other GABAB subunits, no response to GABAB ligands could be detected. Therefore the function of this protein remains to be elucidated.[2]
References
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Further reading
- Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241 Freely accessible. PMID 12477932.
- Calver AR, Michalovich D, Testa TT; et al. (2003). "Molecular cloning and characterisation of a novel GABAB-related G-protein coupled receptor". Brain Res. Mol. Brain Res. 110 (2): 305–17. doi:10.1016/S0169-328X(02)00662-9. PMID 12591167.
- Vassilatis DK, Hohmann JG, Zeng H; et al. (2003). "The G protein-coupled receptor repertoires of human and mouse". Proc. Natl. Acad. Sci. U.S.A. 100 (8): 4903–8. doi:10.1073/pnas.0230374100. PMC 153653 Freely accessible. PMID 12679517.
- Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 Freely accessible. PMID 15489334.
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- ↑ "Entrez Gene: GPR156 G protein-coupled receptor 156".
- ↑ Calver AR, Michalovich D, Testa TT, Robbins MJ, Jaillard C, Hill J, Szekeres PG, Charles KJ, Jourdain S, Holbrook JD, Boyfield I, Patel N, Medhurst AD, Pangalos MN (2003). "Molecular cloning and characterisation of a novel GABAB-related G-protein coupled receptor". Brain Res. Mol. Brain Res. 110 (2): 305–17. doi:10.1016/S0169-328X(02)00662-9. PMID 12591167.