GPR183
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| G-protein coupled receptor 183 | |||||||||||||
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| Identifiers | |||||||||||||
| Symbols | GPR183; EBI2 | ||||||||||||
| External IDs | OMIM: 605741 MGI: 2442034 HomoloGene: 28066 IUPHAR: EBI2 GeneCards: GPR183 Gene | ||||||||||||
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| RNA expression pattern | |||||||||||||
| 250px | |||||||||||||
| More reference expression data | |||||||||||||
| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 1880 | 321019 | |||||||||||
| Ensembl | ENSG00000169508 | ENSMUSG00000051212 | |||||||||||
| UniProt | P32249 | Q3U6B2 | |||||||||||
| RefSeq (mRNA) | NM_004951 | NM_183031 | |||||||||||
| RefSeq (protein) | NP_004942 | NP_898852 | |||||||||||
| Location (UCSC) | Chr 13: 98.74 - 98.76 Mb | Chr 14: 121.09 - 121.1 Mb | |||||||||||
| PubMed search | [1] | [2] | |||||||||||
G-protein coupled receptor 183 also known as Epstein-Barr virus-induced G-protein coupled receptor 2 (EBI2) is a protein that in humans is encoded by the GPR183 gene.[1][2]
This gene was identified by the up-regulation of its expression upon Epstein-Barr virus infection of primary B lymphocytes. This gene is predicted to encode a G protein-coupled receptor that is most closely related to the thrombin receptor. Expression of this gene was detected in B-lymphocyte cell lines and lymphoid tissues but not in T-lymphocyte cell lines or peripheral blood T lymphocytes. The function of this gene is unknown.[2]
References
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<references />, or <references group="..." />Further reading
- Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1-2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
- Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K; et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1-2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
- Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
- Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
- Rosenkilde MM, Benned-Jensen T, Andersen H; et al. (2006). "Molecular pharmacological phenotyping of EBI2. An orphan seven-transmembrane receptor with constitutive activity". J. Biol. Chem. 281 (19): 13199–208. doi:10.1074/jbc.M602245200. PMID 16540462.
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This article incorporates text from the United States National Library of Medicine, which is in the public domain.
sr:GPR183- ↑ Lua error in package.lua at line 80: module 'Module:Citation/CS1/Suggestions' not found.
- ↑ 2.0 2.1 "Entrez Gene: EBI2 Epstein-Barr virus induced gene 2 (lymphocyte-specific G protein-coupled receptor)".
