VN1R1

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Vomeronasal 1 receptor 1
Identifiers
Symbols	VN1R1; V1RL1; VNR19I1; ZVNH1; ZVNR1
External IDs	OMIM: 605234 HomoloGene: 74336 GeneCards: VN1R1 Gene
Gene Ontology Molecular function • rhodopsin-like receptor activity • receptor activity • pheromone receptor activity Cellular component • membrane • integral to membrane Biological process • signal transduction • G-protein coupled receptor protein signaling pathway • biological_process • response to pheromone Sources: Amigo / EGO
RNA expression pattern
250px
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	57191	n/a
Ensembl	ENSG00000178201	n/a
UniProt	Q9GZP7	n/a
RefSeq (mRNA)	NM_020633	n/a
RefSeq (protein)	NP_065684	n/a
Location (UCSC)	Chr 19: 62.66 - 62.66 Mb	n/a
PubMed search	[1]	n/a

Vomeronasal type-1 receptor 1 is a protein that in humans is encoded by the VN1R1 gene.

Pheromones are chemical signals that elicit specific behavioral responses and physiologic alterations in recipients of the same species. The protein encoded by this gene is similar to pheromone receptors and is primarily localized to the olfactory mucosa. An alternate splice variant of this gene is thought to exist, but its full length nature has not been determined.

Further reading

• Giorgi D, Friedman C, Trask BJ, Rouquier S (2001). "Characterization of nonfunctional V1R-like pheromone receptor sequences in human". Genome Res. 10 (12): 1979–85. doi:10.1101/gr.10.12.1979. PMC 313059 Freely accessible. PMID 11116092. CS1 maint: Multiple names: authors list (link)
• Pantages E, Dulac C (2001). "A novel family of candidate pheromone receptors in mammals". Neuron. 28 (3): 835–45. doi:10.1016/S0896-6273(00)00157-4. PMID 11163270. 
• Takeda S, Kadowaki S, Haga T; et al. (2002). "Identification of G protein-coupled receptor genes from the human genome sequence". FEBS Lett. 520 (1-3): 97–101. doi:10.1016/S0014-5793(02)02775-8. PMID 12044878. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241 Freely accessible. PMID 12477932. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Zhang J, Webb DM (2003). "Evolutionary deterioration of the vomeronasal pheromone transduction pathway in catarrhine primates". Proc. Natl. Acad. Sci. U.S.A. 100 (14): 8337–41. doi:10.1073/pnas.1331721100. PMC 166230 Freely accessible. PMID 12826614. 
• Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 Freely accessible. PMID 15489334. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Mitropoulos C, Papachatzopoulou A, Menounos PG; et al. (2007). "Association study of human VN1R1 pheromone receptor gene alleles and gender". Genet. Test. 11 (2): 128–32. doi:10.1089/gte.2006.0516. PMID 17627382. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.