Formyl peptide receptor 3
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Formyl peptide receptor 3 | |||||||||||||
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Identifiers | |||||||||||||
Symbols | FPR3; FPRL2; FPRH1; FPRH2; FML2_HUMAN; FMLPY; RMLP-R-I | ||||||||||||
External IDs | OMIM: 136539 MGI: 1194495 HomoloGene: 40605 IUPHAR: FPR3 GeneCards: FPR3 Gene | ||||||||||||
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RNA expression pattern | |||||||||||||
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More reference expression data | |||||||||||||
Orthologs | |||||||||||||
Species | Human | Mouse | |||||||||||
Entrez | 2359 | 14294 | |||||||||||
Ensembl | ENSG00000187474 | ENSMUSG00000079700 | |||||||||||
UniProt | P25089 | O08790 | |||||||||||
RefSeq (mRNA) | NM_002030 | NM_008042 | |||||||||||
RefSeq (protein) | NP_002021 | NP_032068 | |||||||||||
Location (UCSC) | Chr 19: 56.99 - 57.02 Mb | Chr 17: 18.02 - 18.11 Mb | |||||||||||
PubMed search | [1] | [2] |
N-formyl peptide receptor 3 is a protein that in humans is encoded by the FPR3 gene.[1][2][3]
See also
References
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External links
- "Formylpeptide Receptors: FPRL2". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology.
Further reading
- Christophe T, Karlsson A, Dugave C; et al. (2001). "The synthetic peptide Trp-Lys-Tyr-Met-Val-Met-NH2 specifically activates neutrophils through FPRL1/lipoxin A4 receptors and is an agonist for the orphan monocyte-expressed chemoattractant receptor FPRL2". J. Biol. Chem. 276 (24): 21585–93. doi:10.1074/jbc.M007769200. PMID 11285256.
- Yang D, Chen Q, Gertz B; et al. (2002). "Human dendritic cells express functional formyl peptide receptor-like-2 (FPRL2) throughout maturation". J. Leukoc. Biol. 72 (3): 598–607. PMID 12223529.
- Christophe T, Karlsson A, Rabiet MJ; et al. (2002). "Phagocyte activation by Trp-Lys-Tyr-Met-Val-Met, acting through FPRL1/LXA4R, is not affected by lipoxin A4". Scand. J. Immunol. 56 (5): 470–6. doi:10.1046/j.1365-3083.2002.01149.x. PMID 12410796.
- Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
- Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Ernst S, Lange C, Wilbers A; et al. (2004). "An annexin 1 N-terminal peptide activates leukocytes by triggering different members of the formyl peptide receptor family". J. Immunol. 172 (12): 7669–76. PMID 15187149.
- Harada M, Habata Y, Hosoya M; et al. (2004). "N-Formylated humanin activates both formyl peptide receptor-like 1 and 2". Biochem. Biophys. Res. Commun. 324 (1): 255–61. doi:10.1016/j.bbrc.2004.09.046. PMID 15465011.
- Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
- Kang HK, Lee HY, Kim MK; et al. (2005). "The synthetic peptide Trp-Lys-Tyr-Met-Val-D-Met inhibits human monocyte-derived dendritic cell maturation via formyl peptide receptor and formyl peptide receptor-like 2". J. Immunol. 175 (2): 685–92. PMID 16002663.
- Lee HY, Lee SY, Shin EH; et al. (2007). "F2L, a peptide derived from heme-binding protein, inhibits formyl peptide receptor-mediated signaling". Biochem. Biophys. Res. Commun. 359 (4): 985–90. doi:10.1016/j.bbrc.2007.06.001. PMID 17577578.
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- ↑ "Entrez Gene: FPRL2 formyl peptide receptor-like 2".