GPR177
From Self-sufficiency
| edit |
| G protein-coupled receptor 177 | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| Symbols | GPR177; MRP; C1orf139; FLJ23091; MGC131760; MGC14878; WLS | ||||||||
| External IDs | MGI: 1915401 HomoloGene: 11779 GeneCards: GPR177 Gene | ||||||||
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| RNA expression pattern | |||||||||
| 250px | |||||||||
| More reference expression data | |||||||||
| Orthologs | |||||||||
| Species | Human | Mouse | |||||||
| Entrez | 79971 | 68151 | |||||||
| Ensembl | ENSG00000116729 | ENSMUSG00000028173 | |||||||
| UniProt | Q5T9L3 | Q8CDZ6 | |||||||
| RefSeq (mRNA) | NM_001002292 | NM_026582 | |||||||
| RefSeq (protein) | NP_001002292 | NP_080858 | |||||||
| Location (UCSC) | Chr 1: 68.34 - 68.47 Mb | Chr 3: 159.78 - 159.87 Mb | |||||||
| PubMed search | [1] | [2] | |||||||
G protein-coupled receptor 177 (GPR177), commonly known as Wntless, is a human gene[1] that encodes a receptor for Wnt proteins in Wnt-secreting cells.[2]
Wntless was recently shown to be a cargo for the retromer complex.[2]
References
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- Gregory SG, Barlow KF, McLay KE; et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. doi:10.1038/nature04727. PMID 16710414.
- Bänziger C, Soldini D, Schütt C; et al. (2006). "Wntless, a conserved membrane protein dedicated to the secretion of Wnt proteins from signaling cells". Cell. 125 (3): 509–22. doi:10.1016/j.cell.2006.02.049. PMID 16678095.
- Otsuki T, Ota T, Nishikawa T; et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Res. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743.
- Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 Freely accessible. PMID 15489334.
- Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Clark HF, Gurney AL, Abaya E; et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697 Freely accessible. PMID 12975309.
- Matsuda A, Suzuki Y, Honda G; et al. (2003). "Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways". Oncogene. 22 (21): 3307–18. doi:10.1038/sj.onc.1206406. PMID 12761501.
- Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241 Freely accessible. PMID 12477932.
See also
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This article incorporates text from the United States National Library of Medicine, which is in the public domain.
sr:GPR177- ↑ "Entrez Gene: GPR177 G protein-coupled receptor 177".
- ↑ 2.0 2.1 Lua error in package.lua at line 80: module 'Module:Citation/CS1/Suggestions' not found.
