OPN3

edit

Opsin 3 (encephalopsin, panopsin)
Identifiers
Symbols	OPN3; ECPN
External IDs	OMIM: 606695 MGI: 1338022 HomoloGene: 40707 IUPHAR: OPN3 GeneCards: OPN3 Gene
Gene Ontology Molecular function • rhodopsin-like receptor activity • receptor activity • G-protein coupled photoreceptor activity Cellular component • integral to plasma membrane • membrane • integral to membrane Biological process • signal transduction • G-protein coupled receptor protein signaling pathway • visual perception • phototransduction • protein-chromophore linkage • regulation of circadian rhythm • response to stimulus Sources: Amigo / EGO
RNA expression pattern
250px
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	23596	13603
Ensembl	ENSG00000054277	ENSMUSG00000026525
UniProt	Q9H1Y3	Q3KR48
RefSeq (mRNA)	NM_001030011	NM_010098
RefSeq (protein)	NP_001025182	NP_034228
Location (UCSC)	Chr 1: 239.82 - 239.87 Mb	Chr 1: 177.5 - 177.53 Mb
PubMed search	[1]	[2]

Opsin-3 is a protein that, in humans, is encoded by the OPN3 gene. Alternative splicing of this gene results in multiple transcript variants encoding different protein isoforms.

Function

Opsins are members of the G protein-coupled receptor superfamily. In addition to the visual opsins, mammals possess several photoreceptive non-visual opsins that are expressed in tissues. outside the eye. The opsin-3 gene is strongly expressed in brain and testis and weakly expressed in liver, placenta, heart, lung, skeletal muscle, kidney, and pancreas. The gene may also be expressed in the retina. The protein has the canonical features of a photoreceptive opsin protein.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.